CD41/Integrin alpha 2b抗体-抗体-抗体-生物在线
CD41/Integrin alpha 2b抗体

CD41/Integrin alpha 2b抗体

商家询价

产品名称： CD41/Integrin alpha 2b抗体

英文名称： CD41/Integrin alpha 2bAntibody

产品编号： XY18308-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CD41/INTEGRIN ALPHA 2B抗体

 

Applications
Tested Applications: ELISA
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Recommended dilution  
A CD41/INTEGRIN ALPHA 2B抗体pplication key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Caculated Molecular
Weight:		 113 kDa Observed Molecular 
Weight:		  
GenbankNo BC126442 GeneID: 3674
Symbol ITGA2B Synonyms ITGA2B, GTA, GP2B, CD41B, GPIIb
Background CD41/INTEGRIN ALPHA 2B抗体

CD41, also named as ITGA2B CD41B GPIIb GTA and HPA3, is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands and the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. CD41 is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. CD41 chain interacts with the ITGB3 (CD61) to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation. CD41/INTEGRIN ALPHA 2B抗体

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